Reovirus Preferentially Infects the Basolateral Surface and Is Released from the Apical Surface of Polarized Human Respiratory Epithelial Cells

Mammalian reoviruses infect respiratory and gastrointestinal epithelia and cause disease in neonates. Junctional adhesion molecule-A (JAM-A) is a serotype-independent receptor for reovirus. JAM-A localizes to tight junctions and contributes to paracellular permeability in polarized epithelia. To inv...

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Hauptverfasser: Excoffon, Katherine J. D. A., Guglielmi, Kristen M., Wetzel, J. Denise, Gansemer, Nicholas D., Campbell, Jacquelyn A., Dermody, Terence S., Zabner, Joseph
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2008
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2736797/
https://ncbi.nlm.nih.gov/pubmed/18419529
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1086/529515
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