Podocyte Glutamatergic Signaling Contributes to the Function of the Glomerular Filtration Barrier

Podocytes possess the complete machinery for glutamatergic signaling, raising the possibility that neuron-like signaling contributes to glomerular function. To test this, we studied mice and cells lacking Rab3A, a small GTPase that regulates glutamate exocytosis. In addition, we blocked the glutamat...

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Hauptverfasser: Giardino, Laura, Armelloni, Silvia, Corbelli, Alessandro, Mattinzoli, Deborah, Zennaro, Cristina, Guerrot, Dominique, Tourrel, Fabien, Ikehata, Masami, Li, Min, Berra, Silvia, Carraro, Michele, Messa, Piergiorgio, Rastaldi, Maria P.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society of Nephrology 2009
Schlagworte:
Basic Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2736779/
https://ncbi.nlm.nih.gov/pubmed/19578006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2008121286
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