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Campylobacter Jejuni PglH is a Single Active Site Processive Polymerase that Utilizes Product Inhibition to Limit Sequential Glycosyl Transfer Reactions

Asparagine-linked protein glycosylation is essential for the virulence of the human gut mucosal pathogen Campylobacter jejuni. The heptasaccharide that is transferred to proteins is biosynthesized via the glycosyltransferase-catalyzed addition of sugar units to an undecaprenyl diphosphate-linked car...

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Détails bibliographiques
Auteurs principaux: Troutman, Jerry M., Imperiali, Barbara
Format: Artigo
Langue:Inglês
Publié: 2009
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2736683/
https://ncbi.nlm.nih.gov/pubmed/19159314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi802284d
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