The 3′ Region of the Chicken Hypersensitive Site-4 Insulator Has Properties Similar to Its Core and Is Required for Full Insulator Activity

Chromatin insulators separate active transcriptional domains and block the spread of heterochromatin in the genome. Studies on the chicken hypersensitive site-4 (cHS4) element, a prototypic insulator, have identified CTCF and USF-1/2 motifs in the proximal 250 bp of cHS4, termed the “core”, which pr...

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Bibliographic Details
Main Authors: Arumugam, Paritha I., Urbinati, Fabrizia, Velu, Chinavenmeni S., Higashimoto, Tomoyasu, Grimes, H. Leighton, Malik, Punam
Format: Artigo
Language:Inglês
Published: Public Library of Science 2009
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2736623/
https://ncbi.nlm.nih.gov/pubmed/19746166
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0006995
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