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A pseudobond parametrization for improved electrostatics in quantum mechanical∕molecular mechanical simulations of enzymes

The pseudobond method is used in quantum mechanical∕molecular mechanical (QM∕MM) simulations in which a covalent bond connects the quantum mechanical and classical subsystems. In this method, the molecular mechanical boundary atom is replaced by a special quantum mechanical atom with one free valenc...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Parks, Jerry M., Hu, Hao, Cohen, Aron J., Yang, Weitao
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Institute of Physics 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2736614/
https://ncbi.nlm.nih.gov/pubmed/19045175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1063/1.2994288
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