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Reversible Thiazolidine Exchange: A New Reaction Suitable for Dynamic Combinatorial Chemistry

[Image: see text] New dynamic combinatorial libraries (DCLs) were generated using the reversible aminothiol exchange reaction of thiazolidines and aromatic aldehydes. The reaction proceeded in aqueous buffered media at pH 4 and room temperature to generate thermodynamically controlled mixtures of he...

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Detalhes bibliográficos
Main Authors: Saiz, Cecilia, Wipf, Peter, Manta, Eduardo, Mahler, Graciela
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2736333/
https://ncbi.nlm.nih.gov/pubmed/19585999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol901104a
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