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NF-κB and Phosphatidylinositol 3-Kinase Activity Mediates the HCMV-Induced Atypical M1/M2 Polarization of Monocytes

Human cytomegalovirus infection of monocytes stimulates a unique monocyte differentiation reprogramming resulting in polarization towards an M1 pro-inflammatory macrophage that simultaneously exhibits characteristics of an M2 anti-inflammatory macrophage. Our laboratory has previously shown that HCM...

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Autors principals: Chan, Gary, Bivins-Smith, Elizabeth R., Smith, M. Shane, Yurochko, Andrew D.
Format: Artigo
Idioma:Inglês
Publicat: 2009
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2736317/
https://ncbi.nlm.nih.gov/pubmed/19427341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virusres.2009.04.026
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