General Transcription Factor IIA-γ Increases Osteoblast-specific Osteocalcin Gene Expression via Activating Transcription Factor 4 and Runt-related Transcription Factor 2

ATF4 (activating transcription factor 4) is an osteoblast-enriched transcription factor that regulates terminal osteoblast differentiation and bone formation. ATF4 knock-out mice have reduced bone mass (severe osteoporosis) throughout life. Runx2 (runt-related transcription factor 2) is a runt domai...

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Bibliographic Details
Main Authors: Yu, Shibing, Jiang, Yu, Galson, Deborah L., Luo, Min, Lai, Yumei, Lu, Yi, Ouyang, Hong-Jiao, Zhang, Jian, Xiao, Guozhi
Format: Artigo
Language:Inglês
Published: 2008
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2736298/
https://ncbi.nlm.nih.gov/pubmed/18171674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M705653200
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