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RNA interference for apoptosis signal-regulating kinase-1 (ASK-1) rescues photoreceptor death in the rd1 mouse

PURPOSE: To evaluate whether RNA interference against apoptosis signal-regulating kinase-1 (ASK-1), a gene involved in stress-induced apoptosis, inhibits photoreceptor death in retinal degeneration 1 (rd1) mice. METHODS: Retinal explants from rd1 mice were subjected to organ cultures on postnatal da...

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Detalhes bibliográficos
Main Authors: Sekimukai, Daisuke, Honda, Shigeru, Negi, Akira
Formato: Artigo
Idioma:Inglês
Publicado em: Molecular Vision 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2736151/
https://ncbi.nlm.nih.gov/pubmed/19727340
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