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The Glucose Transporter 2 Undergoes Plasma Membrane Endocytosis and Lysosomal Degradation in a Secretagogue-Dependent Manner

In β-cells of the pancreas, the glucose transporter (GLUT)-2 facilitative glucose transporter protein is localized to the plasma membrane and functions as part of the glucose sensing mechanism for the stimulation of insulin secretion. We observed that expressed GLUT2 protein in the cultured Min6B1 c...

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Detalhes bibliográficos
Main Authors: Hou, June Chunqiu, Williams, Dumaine, Vicogne, Jérôme, Pessin, Jeffrey E.
Formato: Artigo
Idioma:Inglês
Publicado em: The Endocrine Society 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2736072/
https://ncbi.nlm.nih.gov/pubmed/19477941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2008-1685
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