Generation of mature human myelomonocytic cells through expansion and differentiation of pluripotent stem cell–derived lin(–)CD34(+)CD43(+)CD45(+) progenitors

Basic research into human mature myelomonocytic cell function, myeloid lineage diversification and leukemic transformation, and assessment of myelotoxicity in preclinical drug development requires a constant supply of donor blood or bone marrow samples and laborious purification of mature myeloid ce...

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Bibliographic Details
Main Authors: Choi, Kyung-Dal, Vodyanik, Maxim A., Slukvin, Igor I.
Format: Artigo
Language:Inglês
Published: American Society for Clinical Investigation 2009
Subjects:
Technical Advance
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2735935/
https://ncbi.nlm.nih.gov/pubmed/19726877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI38591
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