Transcriptional Regulation of Vascular Endothelial Growth Factor C by Oxidative and Thermal Stress Is Mediated by Lens Epithelium-Derived Growth Factor/p75

Vascular endothelial growth factor C (VEGF-C) plays a critical role in tumor lymphangiogenesis and lymph node metastasis. We report here that VEGF-C expression is regulated by microenvironmental stress including hyperthermia and oxidative stress. Furthermore, we show that this stress response is med...

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Bibliographic Details
Main Authors: Cohen, Batya, Addadi, Yoseph, Sapoznik, Stav, Meir, Gila, Kalchenko, Vyacheslav, Harmelin, Alon, Ben-Dor, Shifra, Neeman, Michal
Format: Artigo
Language:Inglês
Published: Neoplasia Press Inc. 2009
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2735804/
https://ncbi.nlm.nih.gov/pubmed/19724686
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