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Shiga Toxin and Lipopolysaccharide Induce Platelet-Leukocyte Aggregates and Tissue Factor Release, a Thrombotic Mechanism in Hemolytic Uremic Syndrome

BACKGROUND: Aggregates formed between leukocytes and platelets in the circulation lead to release of tissue factor (TF)–bearing microparticles contributing to a prothrombotic state. As enterohemorrhagic Escherichia coli (EHEC) may cause hemolytic uremic syndrome (HUS), in which microthrombi cause ti...

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Bibliografski detalji
Glavni autori: Ståhl, Anne-lie, Sartz, Lisa, Nelsson, Anders, Békássy, Zivile D., Karpman, Diana
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2009
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2735777/
https://ncbi.nlm.nih.gov/pubmed/19750223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0006990
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