Overexpressed cyclophilin B suppresses apoptosis associated with ROS and Ca(2+) homeostasis after ER stress

Prolonged accumulation of misfolded proteins in the endoplasmic reticulum (ER) results in ER stress-mediated apoptosis. Cyclophilins are protein chaperones that accelerate the rate of protein folding through their peptidyl-prolyl cis-trans isomerase (PPIase) activity. In this study, we demonstrated...

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Detalhes bibliográficos
Main Authors: Kim, Jinhwan, Choi, Tae Gyu, Ding, Yan, Kim, Yeonghwan, Ha, Kwon Soo, Lee, Kyung Ho, Kang, Insug, Ha, Joohun, Kaufman, Randal J., Lee, Jinhwa, Choe, Wonchae, Kim, Sung Soo
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2735721/
https://ncbi.nlm.nih.gov/pubmed/18946027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.028654
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