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ZO-1 Stabilizes the Tight Junction Solute Barrier through Coupling to the Perijunctional Cytoskeleton

ZO-1 binds numerous transmembrane and cytoplasmic proteins and is required for assembly of both adherens and tight junctions, but its role in defining barrier properties of an established tight junction is unknown. We depleted ZO-1 in MDCK cells using siRNA methods and observed specific defects in t...

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Bibliografiset tiedot
Päätekijät: Van Itallie, Christina M., Fanning, Alan S., Bridges, Arlene, Anderson, James M.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: The American Society for Cell Biology 2009
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Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2735491/
https://ncbi.nlm.nih.gov/pubmed/19605556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E09-04-0320
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