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Budding Yeast SSD1-V Regulates Transcript Levels of Many Longevity Genes and Extends Chronological Life Span in Purified Quiescent Cells

Ssd1 is an RNA-binding protein that affects literally hundreds of different processes and is polymorphic in both wild and lab yeast strains. We have used transcript microarrays to compare mRNA levels in an isogenic pair of mutant (ssd1-d) and wild-type (SSD1-V) cells across the cell cycle. We find t...

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Detalhes bibliográficos
Main Authors: Li, Lihong, Lu, Yong, Qin, Li-Xuan, Bar-Joseph, Ziv, Werner-Washburne, Margaret, Breeden, Linda L.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2735484/
https://ncbi.nlm.nih.gov/pubmed/19570907
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E09-04-0347
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