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The Insulin-like Growth Factor (IGF)-I E-Peptides Modulate Cell Entry of the Mature IGF-I Protein

Insulin-like growth factor (IGF)-I is a critical protein for cell development and growth. Alternative splicing of the igf1 gene gives rise to multiple isoforms. In rodents, proIGF-IA and proIGF-IB have different carboxy-terminal extensions called the E-peptides (EA and EB) and upon further posttrans...

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Bibliografiske detaljer
Main Authors: Pfeffer, Lindsay A., Brisson, Becky K., Lei, Hanqin, Barton, Elisabeth R.
Format: Artigo
Sprog:Inglês
Udgivet: The American Society for Cell Biology 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2735480/
https://ncbi.nlm.nih.gov/pubmed/19605562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E08-12-1202
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