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Loss of Bmx Non-Receptor Tyrosine Kinase Prevents Pressure Overload-Induced Cardiac Hypertrophy

Bmx non-receptor tyrosine kinase has an established role in endothelial and lymphocyte signaling, however its role in the heart is unknown. To determine whether Bmx participates in cardiac growth, we subjected mice deficient in the molecule (Bmx KO mice) to transverse aortic constriction (TAC). In c...

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Detalhes bibliográficos
Main Authors: Mitchell-Jordan, Scherise A., Holopainen, Tanja, Ren, Shuxun, Wang, Sujing, Warburton, Sarah, Zhang, Michael J., Alitalo, Kari, Wang, Yibin, Vondriska, Thomas M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2735252/
https://ncbi.nlm.nih.gov/pubmed/18988895
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.108.186577
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