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Structural basis for exon recognition by a group II intron

Free group II introns are infectious retroelements that can bind and insert themselves into RNA and DNA molecules via reverse-splicing. Here we report the 3.4Å crystal structure of a complex between an oligonucleotide target substrate and a group IIC intron, as well as the refined free intron struct...

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Autori principali: Toor, Navtej, Rajashankar, Kanagalaghatta, Keating, Kevin, Pyle, Anna Marie
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2735234/
https://ncbi.nlm.nih.gov/pubmed/18953333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.1509
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