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Genetic evidence supporting a critical role of endothelial caveolin-1 during the progression of atherosclerosis

The accumulation of LDL-derived cholesterol in the artery wall is the initiating event that causes atherosclerosis. However, the mechanisms that lead to the initiation of atherosclerosis are still poorly understood. Here, by using endothelial cell-specific transgenesis of the caveolin-1 (Cav-1) gene...

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Detalhes bibliográficos
Main Authors: Fernández-Hernando, Carlos, Yu, Jun, Suárez, Yajaira, Rahner, Christoph, Dávalos, Alberto, Lasunción, Miguel A., Sessa, William C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2735117/
https://ncbi.nlm.nih.gov/pubmed/19583953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2009.06.003
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