Thyroid cancer in a patient with a germline MSH2 mutation. Case report and review of the Lynch syndrome expanding tumour spectrum

Lynch syndrome (HNPCC) is a dominantly inherited disorder characterized by germline defects in DNA mismatch repair (MMR) genes and the development of a variety of cancers, predominantly colorectal and endometrial. We present a 44-year-old woman who was shown to carry the truncating MSH2 gene mutatio...

Full description

Saved in:
Bibliographic Details
Main Authors: Stulp, Rein P, Herkert, Johanna C, Karrenbeld, Arend, Mol, Bart, Vos, Yvonne J, Sijmons, Rolf H
Format: Artigo
Language:Inglês
Published: BioMed Central 2008
Subjects:
Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2735069/
https://ncbi.nlm.nih.gov/pubmed/19706203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1897-4287-6-1-15
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items