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Dimerization of Tetherin Is Not Essential for Its Antiviral Activity against Lassa and Marburg Viruses

Tetherin (also known as BST2, CD317 or HM1.24) has recently been reported to inhibit a wide range of viruses. However, the antiviral mechanism of action of tetherin has not been determined. Both ends of the tetherin molecule are associated with the plasma membrane and it forms a homodimer. Therefore...

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Detalhes bibliográficos
Main Authors: Sakuma, Toshie, Sakurai, Akira, Yasuda, Jiro
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2735005/
https://ncbi.nlm.nih.gov/pubmed/19742323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0006934
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