Hepatic inflammation mediated by hepatitis C virus core protein is ameliorated by blocking complement activation

BACKGROUND: The pathogenesis of inflammation and fibrosis in chronic hepatitis C virus (HCV) infection remains unclear. Transgenic mice with constitutive HCV core over-expression display steatosis only. While the reasons for this are unclear, it may be important that core protein production in these...

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Main Authors: Chang, Ming-Ling, Yeh, Chau-Ting, Lin, Deng-Yn, Ho, Yu-Pin, Hsu, Chen-Ming, Bissell, D Montgomery
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2009
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2734540/
https://ncbi.nlm.nih.gov/pubmed/19664232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1755-8794-2-51
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