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The end defines the means: How the 5′ phosphorylation state controls bacterial mRNA decay
Bacterial mRNAs begin with a triphosphate on the first transcribed nucleotide, but the endonuclease long thought to initiate mRNA decay in E. coli (RNase E) only works well on RNA with a 5′ monophosphate. The first committed step in the degradation of mRNA in that organism now appears to be the conv...
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2007
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2734461/ https://ncbi.nlm.nih.gov/pubmed/17710097 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio0907-535 |
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