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Comparison of Power Between Randomized Discontinuation Design and Upfront Randomization Design on Progression-Free Survival
PURPOSE: Enrichment based on molecular characteristics has emerged as an important inclusion criterion in phase II trials of targeted anticancer agents. In this study, we evaluate a well-described method of population enrichment by tumor growth characteristics in the early development stage of targe...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Society of Clinical Oncology
2009
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2734425/ https://ncbi.nlm.nih.gov/pubmed/19636018 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2008.19.6709 |
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