Phase I Dose Escalation, Pharmacokinetic and Pharmacodynamic Study of Naptumomab Estafenatox Alone in Patients With Advanced Cancer and With Docetaxel in Patients With Advanced Non–Small-Cell Lung Cancer

PURPOSE: Two phase I studies were conducted of ABR-217620 alone or in combination with docetaxel. This is a recombinant fusion protein consisting of a mutated variant of the superantigen staphylococcal enterotoxin E (SEA/E-120) linked to fragment antigen binding moiety of a monoclonal antibody recog...

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Detalhes bibliográficos
Main Authors: Borghaei, Hossein, Alpaugh, Katherine, Hedlund, Gunnar, Forsberg, Göran, Langer, Corey, Rogatko, Andre, Hawkins, Robert, Dueland, Svein, Lassen, Ulrik, Cohen, Roger B.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Clinical Oncology 2009
Assuntos:
Original Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2734423/
https://ncbi.nlm.nih.gov/pubmed/19636016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2008.20.2515
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