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Problems and Solutions for Estimating Indel Rates and Length Distributions
Insertions and deletions (indels) are fundamental but understudied components of molecular evolution. Here we present an expectation–maximization algorithm built on a pair hidden Markov model that is able to properly handle indels in neutrally evolving DNA sequences. From a data set of orthologous i...
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Oxford University Press
2009
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| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2734402/ https://ncbi.nlm.nih.gov/pubmed/19042944 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/molbev/msn275 |
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