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Identification of Thioredoxin-2 as a Regulator of the Mitochondrial Permeability Transition

Thioredoxin-2 (Trx2) is a multifunctional, mitochondria-specific protein, which inhibits cell death. The mitochondrial permeability transition (MPT) is a distinct mechanism for cell death activated by oxidants and linked to both necrotic and apoptotic morphologies. We studied mitochondria from Trx2...

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Detalhes bibliográficos
Main Authors: He, Min, Cai, Jiyang, Go, Young-Mi, Johnson, Jennifer M., Martin, W. David, Hansen, Jason M., Jones, Dean P.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2734306/
https://ncbi.nlm.nih.gov/pubmed/18550601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfn116
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