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The Nun Study: Clinically silent AD, neuronal hypertrophy, and linguistic skills in early life

BACKGROUND: It is common to find substantial Alzheimer disease (AD) lesions, i.e., neuritic β-amyloid plaques and neurofibrillary tangles, in the autopsied brains of elderly subjects with normal cognition assessed shortly before death. We have termed this status asymptomatic AD (ASYMAD). We assessed...

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Detalhes bibliográficos
Principais autores: Iacono, D, Markesbery, W R., Gross, M, Pletnikova, O, Rudow, G, Zandi, P, Troncoso, J C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Academy of Neurology 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2734290/
https://ncbi.nlm.nih.gov/pubmed/19587326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/WNL.0b013e3181b01077
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