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The Cellular Phenotype of Roberts Syndrome Fibroblasts as Revealed by Ectopic Expression of ESCO2

Cohesion between sister chromatids is essential for faithful chromosome segregation. In budding yeast, the acetyltransferase Eco1/Ctf7 establishes cohesion during DNA replication in S phase and in response to DNA double strand breaks in G2/M phase. In humans two Eco1 orthologs exist: ESCO1 and ESCO2...

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Detalhes bibliográficos
Main Authors: van der Lelij, Petra, Godthelp, Barbara C., van Zon, Wouter, van Gosliga, Djoke, Oostra, Anneke B., Steltenpool, Jûrgen, de Groot, Jan, Scheper, Rik J., Wolthuis, Rob M., Waisfisz, Quinten, Darroudi, Firouz, Joenje, Hans, de Winter, Johan P.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2734174/
https://ncbi.nlm.nih.gov/pubmed/19738907
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0006936
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