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Learning to Count: Robust Estimates for Labeled Distances between Molecular Sequences

Researchers routinely estimate distances between molecular sequences using continuous-time Markov chain models. We present a new method, robust counting, that protects against the possibly severe bias arising from model misspecification. We achieve this robustness by generalizing the conventional di...

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Hlavní autoři: O'Brien, John D., Minin, Vladimir N., Suchard, Marc A.
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2734148/
https://ncbi.nlm.nih.gov/pubmed/19131426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/molbev/msp003
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