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Overdispersion of the Molecular Clock: Temporal Variation of Gene-Specific Substitution Rates in Drosophila

Simple models of molecular evolution assume that sequences evolve by a Poisson process in which nucleotide or amino acid substitutions occur as rare independent events. In these models, the expected ratio of the variance to the mean of substitution counts equals 1, and substitution processes with a...

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Bibliografiske detaljer
Main Authors: Bedford, Trevor, Hartl, Daniel L.
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2734129/
https://ncbi.nlm.nih.gov/pubmed/18480070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/molbev/msn112
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