Assessment of methylthioadenosine/S-adenosylhomocysteine nucleosidases of Borrelia burgdorferi as targets for novel antimicrobials using a novel high-throughput method

BACKGROUND: Lyme disease is the most prevalent tick-borne disease in the USA with the highest number of cases (27 444 patients) reported by CDC in the year 2007, representing an unprecedented 37% increase from the previous year. The haematogenous spread of Borrelia burgdorferi to various tissues res...

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Main Authors: Cornell, Kenneth A., Primus, Shekerah, Martinez, Jorge A., Parveen, Nikhat
פורמט: Artigo
שפה:Inglês
יצא לאור: Oxford University Press 2009
נושאים:
Original Research
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2734086/
https://ncbi.nlm.nih.gov/pubmed/19376840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jac/dkp129
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