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Salivary mucins inhibit antibacterial activity of the cathelicidin-derived LL-37 peptide but not the cationic steroid CSA-13

OBJECTIVES: Cationic antimicrobial peptides (CAPs) are the effector molecules of innate immunity, similar in potency to classic antibiotics that function in the first-line of defence against infectious agents. The purpose of this study was to investigate the effects of negatively charged mucins on t...

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Библиографические подробности
Главные авторы: Bucki, Robert, Namiot, Dorota B., Namiot, Zbigniew, Savage, Paul B., Janmey, Paul A.
Формат: Artigo
Язык:Inglês
Опубликовано: Oxford University Press 2008
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2734083/
https://ncbi.nlm.nih.gov/pubmed/18456648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jac/dkn176
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