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The Non-Canonical CTD of RNAP-II Is Essential for Productive RNA Synthesis in Trypanosoma brucei
The carboxy-terminal domain (CTD) of the largest subunit (RPB1) of RNA polymerase II (RNAP-II) is essential for gene expression in metazoa and yeast. The canonical CTD is characterized by heptapeptide repeats. Differential phosphorylation of canonical CTD orchestrates transcriptional and co-transcri...
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| Autori principali: | , |
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| Natura: | Artigo |
| Lingua: | Inglês |
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Public Library of Science
2009
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| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2734056/ https://ncbi.nlm.nih.gov/pubmed/19742309 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0006959 |
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