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Reelin acts as a stop signal for radially migrating neurons by inducing phosphorylation of n-cofilin at the leading edge

The extracellular matrix protein Reelin, secreted by Cajal-Retzius (CR) cells in the marginal zone (MZ) of the cerebral cortex, is important for neuronal migration during development. Two lipoprotein receptors for Reelin have been identified, apolipoprotein E receptor 2 (ApoER2) and the very low-den...

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Autors principals: Chai, Xuejun, Förster, Eckart, Zhao, Shanting, Bock, Hans H, Frotscher, Michael
Format: Artigo
Idioma:Inglês
Publicat: Landes Bioscience 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2734053/
https://ncbi.nlm.nih.gov/pubmed/19721896
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