Interleukin 10 suppresses Th17 cytokines secreted by macrophages and T cells

IL-17 and IL-22 are typical cytokines produced by the Th17 T cell subset, but it is unclear if Th17 cytokines can be produced by other cell types. We demonstrate that IL-10-deficient and IL-10R-deficient macrophages stimulated with LPS produce high levels of IL-17 and IL-22. Addition of exogenous IL...

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Main Authors: Gu, Yongpeng, Yang, Jianfei, Ouyang, Xinshou, Liu, Weicheng, Li, Hongxing, Yang, Jianjun, Bromberg, Jonathan, Chen, Shu-Hsia, Mayer, Lloyd, Unkeless, Jay C., Xiong, Huabao
格式: Artigo
語言:Inglês
出版: 2008
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2733944/
https://ncbi.nlm.nih.gov/pubmed/18506885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.200838331
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