Automated 3D mapping of hippocampal atrophy and its clinical correlates in 400 subjects with Alzheimer's disease, mild cognitive impairment, and elderly controls

We used a new method we developed for automated hippocampal segmentation, called the auto context model, to analyze brain MRI scans of 400 subjects from the Alzheimer's disease neuroimaging initiative. After training the classifier on 21 hand‐labeled expert segmentations, we created binary maps...

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Detalhes bibliográficos
Main Authors: Morra, Jonathan H., Tu, Zhuowen, Apostolova, Liana G., Green, Amity E., Avedissian, Christina, Madsen, Sarah K., Parikshak, Neelroop, Hua, Xue, Toga, Arthur W., Jack, Clifford R., Schuff, Norbert, Weiner, Michael W., Thompson, Paul M.
Formato: Artigo
Idioma:Inglês
Publicado em: Wiley Subscription Services, Inc., A Wiley Company 2009
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2733926/
https://ncbi.nlm.nih.gov/pubmed/19172649
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hbm.20708
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