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BDNF-TrkB signaling pathway mediates the induction of epileptiform activity induced by a convulsant drug cyclothiazide

Brain-derived neurotrophic factor (BDNF) and its receptor TrkB play an important function in neuronal development and synaptic plasticity. Recently we have established that cyclothiazide (CTZ) is a novel convulsant drug inducing robust epileptiform activity in hippocampal neurons both in vitro and i...

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Detalhes bibliográficos
Main Authors: Wang, Yun, Qi, Jin-Shun, Kong, Shuzhen, Sun, Yajie, Fan, Jing, Jiang, Min, Chen, Gong
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2733837/
https://ncbi.nlm.nih.gov/pubmed/19393251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2009.04.007
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