Cortical Adenylyl Cyclase 1 Is Required for Thalamocortical Synapse Maturation and Aspects of Layer IV Barrel Development

Experimental evidence from mutant or genetically altered mice indicates that the formation of barrels and the proper maturation of thalamocortical (TC) synapses in the primary somatosensory (barrel) cortex depend on mechanisms mediated by neural activity. Type 1 adenylyl cyclase (AC1), which catalyz...

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Main Authors: Iwasato, Takuji, Inan, Melis, Kanki, Hiroaki, Erzurumlu, Reha S., Itohara, Shigeyoshi, Crair, Michael C.
Format: Artigo
Language:Inglês
Published: Society for Neuroscience 2008
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2733830/
https://ncbi.nlm.nih.gov/pubmed/18524897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0815-08.2008
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