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Low Striatal Glutamate Levels Underlie Cognitive Decline in the Elderly: Evidence from In Vivo Molecular Spectroscopy

Glutamate (Glu), the principal excitatory neurotransmitter of prefrontal cortical efferents, potentially mediates higher order cognitive processes, and its altered availability may underlie mechanisms of age-related decline in frontally based functions. Although animal studies support a role for Glu...

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Detalhes bibliográficos
Main Authors: Zahr, Natalie M., Mayer, Dirk, Pfefferbaum, Adolf, Sullivan, Edith V.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2733311/
https://ncbi.nlm.nih.gov/pubmed/18234683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cercor/bhm250
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