Lack of pharmacokinetic bioequivalence between generic and branded amoxicillin formulations. A post-marketing clinical study on healthy volunteers

AIMS: There are concerns about the quality of generic drugs in the postmarketing setting. The aim was to establish whether two generic formulations of amoxicillin, available on the Italian market, fulfil the criteria for clinical pharmacokinetic bioequivalence vs. the branded drug. METHODS: Two gene...

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Detalhes bibliográficos
Main Authors: Del Tacca, Mario, Pasqualetti, Giuseppe, Di Paolo, Antonello, Virdis, Agostino, Massimetti, Gabriele, Gori, Giovanni, Versari, Daniele, Taddei, Stefano, Blandizzi, Corrado
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2009
Assuntos:
Pharmacokinetics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2732938/
https://ncbi.nlm.nih.gov/pubmed/19660001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2009.03399.x
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