Lack of pharmacokinetic bioequivalence between generic and branded amoxicillin formulations. A post-marketing clinical study on healthy volunteers

AIMS: There are concerns about the quality of generic drugs in the postmarketing setting. The aim was to establish whether two generic formulations of amoxicillin, available on the Italian market, fulfil the criteria for clinical pharmacokinetic bioequivalence vs. the branded drug. METHODS: Two gene...

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Autors principals: Del Tacca, Mario, Pasqualetti, Giuseppe, Di Paolo, Antonello, Virdis, Agostino, Massimetti, Gabriele, Gori, Giovanni, Versari, Daniele, Taddei, Stefano, Blandizzi, Corrado
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Science Inc 2009
Matèries:
Pharmacokinetics
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2732938/
https://ncbi.nlm.nih.gov/pubmed/19660001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2009.03399.x
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