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Long-term safety and efficacy of tocilizumab, an anti-IL-6 receptor monoclonal antibody, in monotherapy, in patients with rheumatoid arthritis (the STREAM study): evidence of safety and efficacy in a 5-year extension study

OBJECTIVES: To evaluate the safety and efficacy of 5-year, long-term tocilizumab monotherapy for patients with rheumatoid arthritis. METHODS: In an open-label, long-term extension trial following an initial 3-month randomised phase II trial, 143 of the 163 patients who participated in the initial bl...

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Detalhes bibliográficos
Main Authors: Nishimoto, N, Miyasaka, N, Yamamoto, K, Kawai, S, Takeuchi, T, Azuma, J
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Group 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2732899/
https://ncbi.nlm.nih.gov/pubmed/19019888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/ard.2008.092866
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