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Postischemic PKC activation rescues retrograde and anterograde long-term memory

Therapeutics for cerebral ischemia/hypoxia, which often results in ischemic stroke in humans, are a global unmet medical need. Here, we report that bryostatin-1, a highly potent protein kinase C (PKC) activator, interrupts pathophysiological molecular cascades and apoptosis triggered by cerebral isc...

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Detalhes bibliográficos
Main Authors: Sun, Miao-Kun, Hongpaisan, Jarin, Alkon, Daniel L.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2732881/
https://ncbi.nlm.nih.gov/pubmed/19667190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0907842106
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