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Postischemic PKC activation rescues retrograde and anterograde long-term memory
Therapeutics for cerebral ischemia/hypoxia, which often results in ischemic stroke in humans, are a global unmet medical need. Here, we report that bryostatin-1, a highly potent protein kinase C (PKC) activator, interrupts pathophysiological molecular cascades and apoptosis triggered by cerebral isc...
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Main Authors: | , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
National Academy of Sciences
2009
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2732881/ https://ncbi.nlm.nih.gov/pubmed/19667190 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0907842106 |
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