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Antiestrogen-resistant subclones of MCF-7 human breast cancer cells are derived from a common monoclonal drug-resistant progenitor

Emergence of antiestrogen-resistant cells in MCF-7 cells during suppression of estrogen signaling is a widely accepted model of acquired breast cancer resistance to endocrine therapy. To obtain insight into the genomic basis of endocrine therapy resistance, we characterized MCF-7 monoclonal sublines...

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Autores principales: Coser, Kathryn R., Wittner, Ben S., Rosenthal, Noël F., Collins, Sabrina C., Melas, Antonia, Smith, Shannon L., Mahoney, Crystal J., Shioda, Keiko, Isselbacher, Kurt J., Ramaswamy, Sridhar, Shioda, Toshi
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2009
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2732824/
https://ncbi.nlm.nih.gov/pubmed/19706540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0907560106
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