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Phosphorylation of the RNA polymerase II C-terminal domain by TFIIH kinase is not essential for transcription of Saccharomyces cerevisiae genome

Ser-5 phosphorylation of the RNA polymerase II (Pol II) C-terminal domain by TFIIH kinase has been implicated in critical steps in mRNA synthesis, such as Pol II promoter escape and mRNA 5′-capping. However, the general requirement and precise role of TFIIH kinase in Pol II transcription still remai...

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Bibliographic Details
Main Authors: Hong, Sun Woo, Hong, Seong Min, Yoo, Jae Wook, Lee, Young Chul, Kim, Soyoun, Lis, John T., Lee, Dong-ki
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2009
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2732804/
https://ncbi.nlm.nih.gov/pubmed/19666497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0903642106
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