Substitution of the α-lactalbumin transcription unit by a CAT cDNA within a BAC clone silenced the locus in transgenic mice without affecting the physically linked Cyclin T1 gene

We recently reported that a goat bacterial artificial chromosome (BAC) clone conferred site-independent expression in transgenic mice of the two loci present within its insert, the ubiquitously expressed Cyclin T1 and the mammary specific β-lactalbumin (αlac) genes. To assess if this vector could ta...

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Detalhes bibliográficos
Main Authors: Solange, Soulier, Marthe, Hudrisier, José, Da Silva Costa, Caroline, Maeder, Céline, Viglietta, Nathalie, Besnard, Jean-Luc, Vilotte
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2003
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2732697/
https://ncbi.nlm.nih.gov/pubmed/12633535
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1297-9686-35-2-239
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