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Pairagon: a highly accurate, HMM-based cDNA-to-genome aligner
Motivation: The most accurate way to determine the intron–exon structures in a genome is to align spliced cDNA sequences to the genome. Thus, cDNA-to-genome alignment programs are a key component of most annotation pipelines. The scoring system used to choose the best alignment is a primary determin...
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Главные авторы: | , , , |
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Формат: | Artigo |
Язык: | Inglês |
Опубликовано: |
Oxford University Press
2009
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Предметы: | |
Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2732315/ https://ncbi.nlm.nih.gov/pubmed/19414532 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btp273 |
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