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Pairagon: a highly accurate, HMM-based cDNA-to-genome aligner

Motivation: The most accurate way to determine the intron–exon structures in a genome is to align spliced cDNA sequences to the genome. Thus, cDNA-to-genome alignment programs are a key component of most annotation pipelines. The scoring system used to choose the best alignment is a primary determin...

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Библиографические подробности
Главные авторы: Lu, David V., Brown, Randall H., Arumugam, Manimozhiyan, Brent, Michael R.
Формат: Artigo
Язык:Inglês
Опубликовано: Oxford University Press 2009
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2732315/
https://ncbi.nlm.nih.gov/pubmed/19414532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btp273
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