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Joint estimation of copy number variation and reference intensities on multiple DNA arrays using GADA

Motivation: The complexity of a large number of recently discovered copy number polymorphisms is much higher than initially thought, thus making it more difficult to detect them in the presence of significant measurement noise. In this scenario, separate normalization and segmentation is prone to le...

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Autors principals: Pique-Regi, Roger, Ortega, Antonio, Asgharzadeh, Shahab
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2732310/
https://ncbi.nlm.nih.gov/pubmed/19276152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btp119
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