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Joint estimation of copy number variation and reference intensities on multiple DNA arrays using GADA

Motivation: The complexity of a large number of recently discovered copy number polymorphisms is much higher than initially thought, thus making it more difficult to detect them in the presence of significant measurement noise. In this scenario, separate normalization and segmentation is prone to le...

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Detalhes bibliográficos
Main Authors: Pique-Regi, Roger, Ortega, Antonio, Asgharzadeh, Shahab
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2732310/
https://ncbi.nlm.nih.gov/pubmed/19276152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btp119
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