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Sparse linear discriminant analysis for simultaneous testing for the significance of a gene set/pathway and gene selection

Motivation: Pathway and gene set-based approaches for the analysis of gene expression profiling experiments have become increasingly popular for addressing problems associated with individual gene analysis. Since most genes are not differently expressed, existing gene set tests, which consider all t...

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Autors principals: Wu, Michael C., Zhang, Lingsong, Wang, Zhaoxi, Christiani, David C., Lin, Xihong
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2732305/
https://ncbi.nlm.nih.gov/pubmed/19168911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btp019
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